Strong interaction is one of the four
fundamental interactions of nature -- in addition to Weak force, Electromagnetism, Gravity. Strongly interacting particles are called hadrons, with the most prominent representatives being protons, neutrons, pions, etc. . Hadrons make up most of the identified matter in the universe. Since the last century we know that most of hadrons are actually excited (short-lived) states. A reasonable analogy to this are the excitations of atoms (see visible spectrum of hydrogen below).
The analogy to atomic system is a crude one: First, the scales of energies in hadronic systems are on the order of 1000 000 000 times larger than those of atomic systems; Second, in contrast to nucleus+electron(s) system the hadrons are constituent of not directly observable building blocks -- quarks and gluons (see Standard Model of Particle Physics). It is believed that understanding the emergence and pattern of the excited energy spectrum of hadrons will help us clarify the nature of strong interaction and, thus, the origin of mass/matter. For the current state of knowledge see the summary by the Particle Data Group.
Theoretical understanding of hadronic spectrum has two indispensable ingredients --
quantum effects and (special) relativity. So far the only way to reconcile both is through the so-called Quantum Field Theory, which for the strong interaction is called
Quantum Chromodynamics (QCD). This theory has several unusual properties rooted in its non-trivial mathematical structure. For example, protons are build up of three quarks, but have a mass hundred times larger than the sum of quark masses. Thus, the largest part of (ordinary matter) mass -- is due to QCD. Unraveling the pattern of excited hadrons is the golden thread through my research, connecting methods from S-matrix theory, effective field theories, numerical techniques of Lattice QCD, statistics, etc..